In situ TE is defined as biomaterial-induced endogenous regeneration directly in the tissue's functional site starting from a resorbable device that gradually transforms into an autologous, homeostatic replacement tissue with the ability to repair, remodel, and grow (Wissing, et al, 2017).
- Wissing et al, doi:10.1038/s41536-017-0023-2The approach of in situ TE is built on the notion that the natural inflammatory response can be harnessed to induce endogenous tissue regeneration. The resorbable immunomodulatory scaffold provides a temporary microenvironment, which functions as an instructive road map for endogenous cells to infiltrate and create new, living, and functional tissue. It is hypothesized that, upon implantation, the scaffold provides support for mature tissue formation and adequate mechanical properties to withstand the hemodynamic loads. Over time, the scaffold should slowly resorb, ultimately resulting in a purely biological structure which has the ability to repair, remodel, and grow.
Our technology parent company, Nanofiber Solutions, is a medical device company with over 10 years experience using a proven technology and manufacturing approach to create unique, proprietary devices, like the Phoenix Wound Matrix, to effectively address heretofore unmet clinical needs.
For more information about how to apply the Phoenix Wound Matrix, click the link below to download our application guidelines.
For information on reimbursement payment and coding information for the Phoenix Wound Matrix, click the link below.
Information on reimbursement in the United States is provided as a courtesy. Due to the rapidly changing nature of the law and Medicare payment policy, and our reliance on information provided by outside sources, the information provided herein does not constitute a guarantee or warranty by RenovoDerm, Inc. that reimbursement will be received. This information is provided "AS IS" and without any other warranty or guarantee, expressed or implied, as to completeness or accuracy or otherwise. This information has been compiled based on data gathered from many primary and secondary sources, including the American Medical Association and certain Medicare contractors.
